Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.4
USERS' SCORE
Good
Based on 7 Reviews
8.2
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Selenium (from SelenoExcell® High Selenium Yeast) (Saccharomyces cerevisiae)
50 mcg
90%
Molybdenum (from molybdenum glycinate chelate)
50 mcg
110%
N-Acetylcysteine (NAC)
600 mg
†
Top Medical Research Studies
8
We studied how selenium-polysaccharides (Se-TP) from green tea could improve chronic fatigue syndrome (CFS) in a rat model. Our experiments revealed that Se-TP significantly enhanced levels of certain substances related to fatigue, indicating improved overall condition. However, while the treatment showed promise in restoring some metabolic markers, the overall efficacy in CFS management remains to be fully affirmed. The changes observed were tied to metabolic pathways involved in steroid hormone biosynthesis and other critical processes.
Read More
8
We explored how sweet corn cob polysaccharide selenium nanoparticles (U-SCPSeNPs) might help alleviate symptoms of chronic fatigue syndrome (CFS). In this study, we used mouse models to test the effects of these nanoparticles, which were created using an ultrasound-assisted method.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
Read More
7
Potential benefits of yeast supplements
We explored the impact of "Nagipol," a supplement made from beer yeasts, on chronic fatigue syndrome (CFS). Our clinical study indicated that "Nagipol" could improve the clinical status of CFS patients. It appears to help enhance cognitive functions and stabilize emotional symptoms while also normalizing certain blood parameters.
While these findings are promising, it’s important to note that further research is needed to fully confirm these benefits, especially regarding its role in diet therapy for individuals dealing with CFS.
While these findings are promising, it’s important to note that further research is needed to fully confirm these benefits, especially regarding its role in diet therapy for individuals dealing with CFS.
Read More
Most Useful Reviews
9
Significant energy boost
2 people found this helpful
Excellent! I have Gilbert's syndrome and take this remedy to enhance liver detoxification. The effects were immediate – my energy levels and performance significantly increased, alleviating my asthenia.
Read More
7.5
Enhanced energy levels
2 people found this helpful
I'm pleased with the good composition, quick delivery, and sturdy packaging of this product. Although the capsules are slightly large, they’re easy to swallow and taste of citrus. I take one daily alongside vitamin D3+K2, magnesium, and vitamin B6. Within ten days of use, I've noticed a marked increase in energy, my headaches have ceased, and I maintain an excellent mood throughout the day. It's especially beneficial for those involved in fitness, sports, or dieting.
Read More
9
Miracle supplement
1 people found this helpful
It is a miraculous product against fatigue. I take one NAC every evening, waking up in great shape and not thinking about going back to bed. If one takes a lot of paracetamol, NAC is the supplement needed to detoxify the liver.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.4
- All Researches
8
We explored how sweet corn cob polysaccharide selenium nanoparticles (U-SCPSeNPs) might help alleviate symptoms of chronic fatigue syndrome (CFS). In this study, we used mouse models to test the effects of these nanoparticles, which were created using an ultrasound-assisted method.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
Read More
8
We studied how selenium-polysaccharides (Se-TP) from green tea could improve chronic fatigue syndrome (CFS) in a rat model. Our experiments revealed that Se-TP significantly enhanced levels of certain substances related to fatigue, indicating improved overall condition. However, while the treatment showed promise in restoring some metabolic markers, the overall efficacy in CFS management remains to be fully affirmed. The changes observed were tied to metabolic pathways involved in steroid hormone biosynthesis and other critical processes.
Read More
7
Beta-glucan alleviates cognitive fatigue
We conducted a rigorous 36-week study with 65 patients diagnosed with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Participants were given either yeast-derived beta-glucan with vitamins or a placebo.
The results revealed that those taking beta-glucan showed notable improvements in cognitive fatigue compared to those on the placebo. This suggests that beta-glucan could be a promising nutritional supplement for easing cognitive symptoms associated with ME/CFS.
However, more research is needed to fully understand its benefits and mechanisms.
The results revealed that those taking beta-glucan showed notable improvements in cognitive fatigue compared to those on the placebo. This suggests that beta-glucan could be a promising nutritional supplement for easing cognitive symptoms associated with ME/CFS.
However, more research is needed to fully understand its benefits and mechanisms.
Read More
7
Potential benefits of yeast supplements
We explored the impact of "Nagipol," a supplement made from beer yeasts, on chronic fatigue syndrome (CFS). Our clinical study indicated that "Nagipol" could improve the clinical status of CFS patients. It appears to help enhance cognitive functions and stabilize emotional symptoms while also normalizing certain blood parameters.
While these findings are promising, it’s important to note that further research is needed to fully confirm these benefits, especially regarding its role in diet therapy for individuals dealing with CFS.
While these findings are promising, it’s important to note that further research is needed to fully confirm these benefits, especially regarding its role in diet therapy for individuals dealing with CFS.
Read More
7
CoQ10 and selenium may benefit ME/CFS
We explored whether combining Coenzyme Q10 and selenium could improve outcomes for individuals with chronic fatigue syndrome (ME/CFS). In this study, 27 patients took an oral supplement for 8 weeks. While we noted improvements in overall fatigue severity and quality of life, sleep disturbances did not show any significant change. Additionally, we found increased antioxidant capacity and decreased inflammatory markers, indicating potential benefits. However, other key biomarkers did not show significant changes. Overall, this suggests that long-term supplementation might help some symptoms in ME/CFS.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Significant energy boost
2 people found this helpful
Excellent! I have Gilbert's syndrome and take this remedy to enhance liver detoxification. The effects were immediate – my energy levels and performance significantly increased, alleviating my asthenia.
Read More
7.5
Enhanced energy levels
2 people found this helpful
I'm pleased with the good composition, quick delivery, and sturdy packaging of this product. Although the capsules are slightly large, they’re easy to swallow and taste of citrus. I take one daily alongside vitamin D3+K2, magnesium, and vitamin B6. Within ten days of use, I've noticed a marked increase in energy, my headaches have ceased, and I maintain an excellent mood throughout the day. It's especially beneficial for those involved in fitness, sports, or dieting.
Read More
9
Miracle supplement
1 people found this helpful
It is a miraculous product against fatigue. I take one NAC every evening, waking up in great shape and not thinking about going back to bed. If one takes a lot of paracetamol, NAC is the supplement needed to detoxify the liver.
Read More
7.5
Fatigue reduction
3 people found this helpful
I enjoy supplements, and while diligently taking vitamins and minerals, I wanted at least one good for beauty and skin. After taking N-acetylcysteine, an amino acid with strong antioxidant effects, I noticed that my fatigue seemed reduced and I fell asleep less during seasonal changes.
Read More
7.5
Increased energy
2 people found this helpful
One of the best. This drug is often unavailable, and I almost hunt for it. I take it several times a year for detox. It contains molybdenum, which enhances the effect! After the course, I always feel a positive effect. My fatigue is gone, and I certainly have more strength and energy!
Read More
Frequently Asked Questions
7.5
Enhanced energy levels
2 people found this helpful
I'm pleased with the good composition, quick delivery, and sturdy packaging of this product. Although the capsules are slightly large, they’re easy to swallow and taste of citrus. I take one daily alongside vitamin D3+K2, magnesium, and vitamin B6. Within ten days of use, I've noticed a marked increase in energy, my headaches have ceased, and I maintain an excellent mood throughout the day. It's especially beneficial for those involved in fitness, sports, or dieting.
9
Significant energy boost
2 people found this helpful
Excellent! I have Gilbert's syndrome and take this remedy to enhance liver detoxification. The effects were immediate – my energy levels and performance significantly increased, alleviating my asthenia.
7.5
Increased energy
2 people found this helpful
One of the best. This drug is often unavailable, and I almost hunt for it. I take it several times a year for detox. It contains molybdenum, which enhances the effect! After the course, I always feel a positive effect. My fatigue is gone, and I certainly have more strength and energy!
6
Reduced fatigue
1 people found this helpful
NAC acts as an AC and expectorates effectively, combined with selenium, which works well with zinc for better interaction and boosts immunity. The quality is excellent, with natural ingredients. The symptoms of fatigue fade, and the frequency of intake depends on individual indicators.
9
Miracle supplement
1 people found this helpful
It is a miraculous product against fatigue. I take one NAC every evening, waking up in great shape and not thinking about going back to bed. If one takes a lot of paracetamol, NAC is the supplement needed to detoxify the liver.
7.5
Fatigue reduction
3 people found this helpful
I enjoy supplements, and while diligently taking vitamins and minerals, I wanted at least one good for beauty and skin. After taking N-acetylcysteine, an amino acid with strong antioxidant effects, I noticed that my fatigue seemed reduced and I fell asleep less during seasonal changes.
7
Beta-glucan alleviates cognitive fatigue
We conducted a rigorous 36-week study with 65 patients diagnosed with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Participants were given either yeast-derived beta-glucan with vitamins or a placebo.
The results revealed that those taking beta-glucan showed notable improvements in cognitive fatigue compared to those on the placebo. This suggests that beta-glucan could be a promising nutritional supplement for easing cognitive symptoms associated with ME/CFS.
However, more research is needed to fully understand its benefits and mechanisms.
The results revealed that those taking beta-glucan showed notable improvements in cognitive fatigue compared to those on the placebo. This suggests that beta-glucan could be a promising nutritional supplement for easing cognitive symptoms associated with ME/CFS.
However, more research is needed to fully understand its benefits and mechanisms.
7
Potential benefits of yeast supplements
We explored the impact of "Nagipol," a supplement made from beer yeasts, on chronic fatigue syndrome (CFS). Our clinical study indicated that "Nagipol" could improve the clinical status of CFS patients. It appears to help enhance cognitive functions and stabilize emotional symptoms while also normalizing certain blood parameters.
While these findings are promising, it’s important to note that further research is needed to fully confirm these benefits, especially regarding its role in diet therapy for individuals dealing with CFS.
While these findings are promising, it’s important to note that further research is needed to fully confirm these benefits, especially regarding its role in diet therapy for individuals dealing with CFS.
8
We explored how sweet corn cob polysaccharide selenium nanoparticles (U-SCPSeNPs) might help alleviate symptoms of chronic fatigue syndrome (CFS). In this study, we used mouse models to test the effects of these nanoparticles, which were created using an ultrasound-assisted method.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
7
CoQ10 and selenium may benefit ME/CFS
We explored whether combining Coenzyme Q10 and selenium could improve outcomes for individuals with chronic fatigue syndrome (ME/CFS). In this study, 27 patients took an oral supplement for 8 weeks. While we noted improvements in overall fatigue severity and quality of life, sleep disturbances did not show any significant change. Additionally, we found increased antioxidant capacity and decreased inflammatory markers, indicating potential benefits. However, other key biomarkers did not show significant changes. Overall, this suggests that long-term supplementation might help some symptoms in ME/CFS.
8
We studied how selenium-polysaccharides (Se-TP) from green tea could improve chronic fatigue syndrome (CFS) in a rat model. Our experiments revealed that Se-TP significantly enhanced levels of certain substances related to fatigue, indicating improved overall condition. However, while the treatment showed promise in restoring some metabolic markers, the overall efficacy in CFS management remains to be fully affirmed. The changes observed were tied to metabolic pathways involved in steroid hormone biosynthesis and other critical processes.
References
- Lacasa M, Alegre-Martin J, Sentañes RS, Varela-Sende L, Jurek J, et al. Yeast Beta-Glucan Supplementation with Multivitamins Attenuates Cognitive Impairments in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. 2023;15. 10.3390/nu15214504
- Dotsenko VA, Mosiĭchuk LV, Paramonov AE. [Biologically active food additives for correction of the chronic fatigue syndrome]. Vopr Pitan. 2004;73:17.
- Wang J, Wang X, Xiu W, Li C, Yu S, et al. Ultrasound-assisted preparation of sweet corn cob polysaccharide selenium nanoparticles alleviates symptoms of chronic fatigue syndrome. Food Funct. 2025;16:133. 10.1039/d4fo04195j
- Castro-Marrero J, Domingo JC, Cordobilla B, Ferrer R, Giralt M, et al. Does Coenzyme Q10 Plus Selenium Supplementation Ameliorate Clinical Outcomes by Modulating Oxidative Stress and Inflammation in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome?. Antioxid Redox Signal. 2022;36:729. 10.1089/ars.2022.0018
- Shao C, Song J, Zhao S, Jiang H, Wang B, et al. Therapeutic Effect and Metabolic Mechanism of A Selenium-Polysaccharide from Green Tea on Chronic Fatigue Syndrome. Polymers (Basel). 2018;10. 10.3390/polym10111269
